BDBM350184 US10208056, Compound 16

SMILES NC(=O)c1cc2c([nH]1)-c1ccncc1OC21CCN(CC1)C1CC1

InChI Key InChIKey=WPXFHTCBJYRTHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350184   

TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350184(US10208056, Compound 16)
Affinity DataIC50:  4.28E+3nMAssay Description:The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350184(US10208056, Compound 16)
Affinity DataIC50:  5.70E+3nMAssay Description:The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent