BDBM350197 US10208056, Compound 29

SMILES CC1(C)Oc2cnccc2-c2[nH]c(C(O)=O)c(Br)c12

InChI Key InChIKey=ZHJUEEVXBXXRCT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350197   

TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350197(US10208056, Compound 29)
Affinity DataIC50:  52.5nMAssay Description:The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-C/Cyclin-dependent kinase 19(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350197(US10208056, Compound 29)
Affinity DataIC50:  205nMAssay Description:The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350197(US10208056, Compound 29)
Affinity DataIC50:  89.3nMAssay Description:The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent