BDBM350265 US10208056, Compound 92

SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCOCC2)n1CCF

InChI Key InChIKey=LAQSEAAEVBHSFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 350265   

TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350265(US10208056, Compound 92)
Affinity DataIC50:  25.6nMAssay Description:The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-C/Cyclin-dependent kinase 8(Homo sapiens (Human))
F.S.P. Cnio

US Patent
LigandPNGBDBM350265(US10208056, Compound 92)
Affinity DataIC50: <1.41nMAssay Description:The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent