BDBM350554 1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,3,4- tetrahydroisoquinolin-7-yl]-3- [4-(methylsulfanyl)phenyl]urea::US10208071, Compound 16::US10434112, Compound 36::US10799518, Compound 36

SMILES CSc1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1

InChI Key InChIKey=NXVCYSRQNARCQL-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 350554   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350554(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  2.50E+3nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350554(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  2.5nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350554(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  3.30nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350554(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  2.5nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350554(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  3.30nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent