BDBM350563 1-{3-(5-fluoropyridin-2-yl)-2- [2-(1H-imidazol-4-yl)ethyl]-1- oxo-1,2,3,4- tetrahydroisoquinolin-7-yl}-3- [4-(methylsulfonyl)phenyl]urea::US10208071, Compound 25::US10434112, Compound 25::US10799518, Compound 25

SMILES CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCc4c[nH]cn4)C(=O)c3c2)c2ccc(F)cn2)cc1

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350563   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350563(1-{3-(5-fluoropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Affinity DataEC50:  1.05E+4nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350563(1-{3-(5-fluoropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Affinity DataEC50:  10.5nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350563(1-{3-(5-fluoropyridin-2-yl)-2- [2-(1H-imidazol-4-y...)
Affinity DataEC50:  10.5nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent