BDBM350579 (+) 1-[(3R)-2-(3- aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,3,4- tetrahydroisoquinolin-7-yl]-3- [4-(methylsulfinyl)phenyl]urea::US10208071, Compound 41::US10434112, Compound 41::US10799518, Compound 41

SMILES CS(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1

InChI Key InChIKey=LBJKHLZSIJUHMM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350579   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350579((+) 1-[(3R)-2-(3- aminopropyl)-3-(4- cyanophenyl)-...)
Affinity DataEC50:  1.06E+4nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350579((+) 1-[(3R)-2-(3- aminopropyl)-3-(4- cyanophenyl)-...)
Affinity DataEC50:  10.6nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350579((+) 1-[(3R)-2-(3- aminopropyl)-3-(4- cyanophenyl)-...)
Affinity DataEC50:  10.6nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent