BDBM350581 1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,3,4- tetrahydroisoquinolin-7-yl]-3- (4-iodophenyl)urea::US10208071, Compound 43::US10434112, Compound 43::US10799518, Compound 43

SMILES NCCCN1C(Cc2ccc(NC(=O)Nc3ccc(I)cc3)cc2C1=O)c1ccc(cc1)C#N

InChI Key InChIKey=ZMOREIVXEGXUHF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 350581   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350581(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  1.37E+4nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350581(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  13.7nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM350581(1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,...)
Affinity DataEC50:  13.7nMAssay Description:HEK-Gα16 cells stably expressing the human FPR2 receptor was utilized. Cells were plated into 384-well poly-D-lysine coated plates at a density ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent