BDBM3511 4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-diamine::CHEMBL328244::PD153035 Analog 10

SMILES Nc1ccc2ncnc(Nc3cccc(c3)C(F)(F)F)c2c1

InChI Key InChIKey=DLVMGJPGJHCIJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3511   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3511(4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-dia...)
Affinity DataIC50:  575nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3511(4-N-[3-(trifluoromethyl)phenyl]quinazoline-4,6-dia...)
Affinity DataIC50:  574nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed