BDBM351157 US9796700, Compound I-258

SMILES COc1cc(ccc1Nc1ncc(C(N)=O)c(Oc2ccccc2NC(=O)C=C)n1)N1CCN(CC1)C(C)=O

InChI Key InChIKey=FFWJOTAEEGGEBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351157   

TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM351157(US9796700, Compound I-258)
Affinity DataIC50: <100nMAssay Description:The protocol below describes continuous-read kinase assays to measure potency of compounds against activated ERK1 enzyme. The mechanics of the assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent