BDBM351662 N-(4-bromo-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(3-fluoroquinolin-5-yl)acetamide::US9796706, Compound 106

SMILES Fc1cnc2cccc(CC(=O)Nc3scc(Br)c3-c3nc[nH]n3)c2c1

InChI Key InChIKey=HDGJMVJJOYGVSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351662   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351662(N-(4-bromo-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl)...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351662(N-(4-bromo-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl)...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351662(N-(4-bromo-3-(1H-1,2,4-triazol-3-yl)thiophen-2-yl)...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent