BDBM35171 indazole-benzimidazole, 7

SMILES COc1ccccc1-c1ccc2c(n[nH]c2c1)-c1nc2c(cccc2[nH]1)N1CCN(C)CC1

InChI Key InChIKey=NYQAYVWQCAKOAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35171   

TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

LigandPNGBDBM35171(indazole-benzimidazole, 7)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:Active cyclin dependent kinase 2 (CDK2) activity was determined by measuring the phosphorylation of Histone type 3 (Sigma H5505), in the presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Pfizer

LigandPNGBDBM35171(indazole-benzimidazole, 7)
Affinity DataIC50:  5.52E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed