BDBM351717 N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide::US9796706, Compound 161

SMILES FC(F)(F)c1ccc2n(CC(=O)Nc3scc(Cl)c3-c3ncn(CCCN4CCOCC4)n3)c(=O)ccc2c1

InChI Key InChIKey=UCCWRYUBEGWTHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351717   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351717(N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-tri...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351717(N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-tri...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Imago Pharmaceuticals

US Patent
LigandPNGBDBM351717(N-(4-chloro-3-(1-(3-morpholinopropyl)-1H-1,2,4-tri...)
Affinity DataIC50: <100nMAssay Description:(1) Assay buffer #1 with 0.0025% Tween and 1 mM DTT was prepared using JNK buffer stock solution.(2) Assay buffer #2 with 0.025% BSA was prepared usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent