BDBM351997 (2S,4R)-1-(2-(3-acetyl- 5-(4-acetylpiperazin-1- yl)-1H-indol-1- yl)acetyl)-N-(2'-chloro- 2-fluorobiphenyl-3-yl)- 4-fluoropyrrolidine-2- carboxamide::US10287301, Compound 16::US10822352, Comp No. 16::US9796741, cmp No. 16

SMILES CC(=O)N1CCN(CC1)c1ccc2n(CC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(c3F)-c3ccccc3Cl)cc(C(C)=O)c2c1

InChI Key InChIKey=AOCGXFJEHSMMKC-HEIROHQZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 351997   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351997((2S,4R)-1-(2-(3-acetyl- 5-(4-acetylpiperazin-1- yl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351997((2S,4R)-1-(2-(3-acetyl- 5-(4-acetylpiperazin-1- yl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM351997((2S,4R)-1-(2-(3-acetyl- 5-(4-acetylpiperazin-1- yl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent