BDBM352185 US9802920, Compound I-9::[5-Amino-1-(2-methoxy-4- phenoxy-phenyl)-1H- pyrazol-4-yl]-(1H-indol-2- yl)-methanone

SMILES COc1cc(Oc2ccccc2)ccc1-n1ncc(C(=O)c2cc3ccccc3[nH]2)c1N

InChI Key InChIKey=NECFQJONEHAJID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352185   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM352185(US9802920, Compound I-9 | [5-Amino-1-(2-methoxy-4-...)
Affinity DataIC50:  146nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent