BDBM352186 US9802920, Compound I-10::[5-Amino-1-(2-hydroxy-4- phenoxy-phenyl)-1H- pyrazol-4-yl]-(1H-indol-2- yl)-methanone

SMILES Nc1c(cnn1-c1ccc(Oc2ccccc2)cc1O)C(=O)c1cc2ccccc2[nH]1

InChI Key InChIKey=DMUGETURCWPDRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 352186   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM352186(US9802920, Compound I-10 | [5-Amino-1-(2-hydroxy-4...)
Affinity DataIC50:  162nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Flouresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent