BDBM35242 3-(phenylsulfonyl)-1H-indole, 18d

SMILES CCNCCc1cccc2[nH]cc(c12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=AVHPWUACYYPSMI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35242   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35242(3-(phenylsulfonyl)-1H-indole, 18d)
Affinity DataKi:  78nM ΔG°:  -10.1kcal/mole IC50:  146nMpH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM35242(3-(phenylsulfonyl)-1H-indole, 18d)
Affinity DataKi:  389nM IC50:  1.03E+3nMAssay Description:Compounds were evaluated the inhibition of [3H] ketanserin binding to membranes from CHO cells, stably transfected with the human 5-HT2A receptor. Da...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed