BDBM352421 N—((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)-1-cyclopentyl-2-oxoethyl)-3-(pyridin-3-yl)benzamide::US9802947, Example C1 (ex. 17 of WO2009/112839)

SMILES Cl[C@H]1CN([C@H]2[C@@H]1OCC2=O)C(=O)[C@@H](NC(=O)c1cccc(c1)-c1cccnc1)C1CCCC1

InChI Key InChIKey=UHLAHTJAHQWXNZ-KZKAQZJJSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 352421   

TargetCathepsin K(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM352421(N—((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H...)
Affinity DataKi:  14.8nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL, CatB) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
GrÜNenthal

US Patent
LigandPNGBDBM352421(N—((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H...)
Affinity DataKi:  82.4nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL, CatB) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent