BDBM353042 N,1,2-trimethyl-5-{7-[(3S)-3-(morpholin-4-ylmethyl)-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]-2-(2-phenylacetyl)-1,2,3,4-tetrahydroisoquinolin-6-yl}-N-phenyl-1H-pyrrole-3-carboxamide::US9809574, Example 117

SMILES CN(C(=O)c1cc(-c2cc3CCN(Cc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)C(=O)Cc2ccccc2)n(C)c1C)c1ccccc1

InChI Key InChIKey=IJYSIEYOTOPMHB-KDXMTYKHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353042   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM353042(N,1,2-trimethyl-5-{7-[(3S)-3-(morpholin-4-ylmethyl...)
Affinity DataIC50:  2.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent