BDBM353069 (2S,4R)-1-(2-(3-acetyl- 5-(4-(methylsulfonyl) piperazin-1-yl)-1H- indol-1-yl)acetyl)-N- (2'-chloro-2- fluorobiphenyl-3-yl)- 4-fluoropyrrolidine-2- carboxamide::US10287301, Compound 33::US10822352, Comp No. 33::US9796741, cmp No. 33

SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)c2ccc(cc12)N1CCN(CC1)S(C)(=O)=O

InChI Key InChIKey=PRCPMFMTBRKSGU-UVDDSOTQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 353069   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM353069((2S,4R)-1-(2-(3-acetyl- 5-(4-(methylsulfonyl) pipe...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM353069((2S,4R)-1-(2-(3-acetyl- 5-(4-(methylsulfonyl) pipe...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM353069((2S,4R)-1-(2-(3-acetyl- 5-(4-(methylsulfonyl) pipe...)
Affinity DataIC50: <1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent