BDBM353767 2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-3,6-dihydropyridin-1(2H)-yl}-1-[3-(hydroxymethyl)azetidin-1-yl]ethanone::US9796708, Example 999

SMILES COc1ccc(F)cc1-c1ccnc2[nH]c(cc12)C1=CCN(CC(=O)N2CC(CO)C2)CC1

InChI Key InChIKey=ABAHFFAFDXIWSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 353767   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM353767(2-{4-[4-(5-fluoro-2-methoxyphenyl)-1H-pyrrolo[2,3-...)
Affinity DataIC50:  14nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent