BDBM354151 1-(2-((2S,4R)-4-fluoro- 2-(4-(5,6,7,8- tetrahydronaphthalen-2- yl)thiazol-2- ylcarbamoyl)pyrrolidin- 1-yl)-2-oxoethyl)-5- (pyridazin-4-yl)-1H- indazole-3-carboxamide::US10287301, Compound 55::US9796741, cmp No. 55

SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2nc(cs2)-c2ccc3CCCCc3c2)c2ccc(cc12)-c1ccnnc1

InChI Key InChIKey=JUSZHPNKSOWIKM-KCWPFWIISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354151   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM354151(1-(2-((2S,4R)-4-fluoro- 2-(4-(5,6,7,8- tetrahydron...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM354151(1-(2-((2S,4R)-4-fluoro- 2-(4-(5,6,7,8- tetrahydron...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent