BDBM354186 (R)-5-(2-(5-fluoro-2- methoxypyridin-3-yl)pyrrolidin-1- yl)-N-(3- hydroxypropyl)pyrazolo[l,5- a]pyrimidine-3-carboxamide::US9796724, Example 148
SMILES COc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)NCCCO)c2n1
InChI Key InChIKey=VTUVGNKQBUVKIW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354186
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Trk enzymatic selectivity was assessed using Omnia™ Kinase Assay reagents from Invitrogen Corp. Enzyme (either TrkA or TrkB from Invitrogen Corp.) an...More data for this Ligand-Target Pair