BDBM354193 1-(2-((2S,4R)-2-(3- chloro-2-(1H-1,2,4- triazol-1- yl)phenylcarbamoyl)-4- fluoropyrrolidin-1-yl)- 2-oxoethyl)-5- (pyridazin-4-yl)-1H- indazole-3-carboxamide::US10287301, Compound 96::US10822352, Comp No. 96::US9796741, cmp No. 96

SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Cl)c2-n2cncn2)c2ccc(cc12)-c1ccnnc1

InChI Key InChIKey=LEGRAROFLIPOMP-VGSWGCGISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 354193   

TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM354193(1-(2-((2S,4R)-2-(3- chloro-2-(1H-1,2,4- triazol-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM354193(1-(2-((2S,4R)-2-(3- chloro-2-(1H-1,2,4- triazol-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor D(Homo sapiens (Human))
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM354193(1-(2-((2S,4R)-2-(3- chloro-2-(1H-1,2,4- triazol-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent