BDBM354309 1-(1-(3-((Dimethylphosphoryl)methyl)phenyl)-3-isopropyl-1H-pyrazol-5-yl)-3-(4-((2-((7-methyl-1H-indazol-5-yl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)urea::US9796742, Example 37
SMILES CC(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(C)c5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1cccc(CP(C)(C)=O)c1
InChI Key InChIKey=BSGXDJPCRLBTKU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 354309
Affinity DataIC50: 70nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
Affinity DataIC50: 4.86E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3?? enzyme isoform (Invitrogen), are evaluated by determining the level of ac...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair