BDBM354330 3-((4-((4-(3-(3-(tert-Butyl)-1-(3-((dimethylphosphoryl)methyl)phenyl)-1H-pyrazol-5-yl)-ureido)naphthalen-1-yl)oxy)pyrimidin-2-yl)amino)-N-(2-morpholinoethyl)-5-(trifluoromethyl)benzamide::US9796742, Example 58
SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4cc(cc(c4)C(F)(F)F)C(=O)NCCN4CCOCC4)n3)c3ccccc23)n(n1)-c1cccc(CP(C)(C)=O)c1
InChI Key InChIKey=AMKRSTDSNXNZMY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 354330
Affinity DataIC50: 84nMAssay Description:The inhibitory activities of test compounds against the p38 MAPKα isoform (MAPK14: Invitrogen), are evaluated indirectly by determining the leve...More data for this Ligand-Target Pair
Affinity DataIC50: 689nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3?? enzyme isoform (Invitrogen), are evaluated by determining the level of ac...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair