BDBM354380 N-(2-ethyl-6-(4- ((tetrahydrofuran-2- yl)methyl)piperazin- 1-yl)imidazo[1,2- b]pyridazin-3-yl)-4- (4-fluorophenyl)-N- methylthiazol-2- amine::US9796719, Compound 48
SMILES CCc1nc2ccc(nn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)N1CCN(CC2CCCO2)CC1
InChI Key InChIKey=VGCXFNKPXLKDIO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354380
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair