BDBM354432 US9796719, Compound 100::[1-(2-Ethyl-3-{[4- (4-fluoro-phenyl)- thiazol-2-yl]- methyl-amino}- imidazo[1,2- b]pyridazin-6-yl)- piperidin-3- ylmethyl]-carbamic acid tert-butyl ester

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(cs1)-c1ccc(F)cc1)N1CCCC(CNC(=O)OC(C)(C)C)C1

InChI Key InChIKey=XXNYAQAQUKWDJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354432   

LigandPNGBDBM354432(US9796719, Compound 100 | [1-(2-Ethyl-3-{[4- (4-fl...)
Affinity DataIC50:  55nMAssay Description:Compound IC50 values are determined in a hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using LPC as substrate.5 μL of a dil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM354432(US9796719, Compound 100 | [1-(2-Ethyl-3-{[4- (4-fl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent