BDBM354506 (S)-2-((2-ethyl-6- (3-(2-(3- hydroxyazetidin-1- yl)-2- oxoethylamino) pyrrolidin-1- yl)imidazo[1,2- b]pyridazin-3- yl)(methyl)amino)- 4-(4- fluorophenyl) thiazole-5- carbonitrile::US9796719, Compound 174
SMILES CCc1nc2ccc(nn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CC[C@@H](C1)NCC(=O)N1CC(O)C1
InChI Key InChIKey=ZNGUALNMUMDXTP-IBGZPJMESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 354506
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: 55nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair