BDBM354506 (S)-2-((2-ethyl-6- (3-(2-(3- hydroxyazetidin-1- yl)-2- oxoethylamino) pyrrolidin-1- yl)imidazo[1,2- b]pyridazin-3- yl)(methyl)amino)- 4-(4- fluorophenyl) thiazole-5- carbonitrile::US9796719, Compound 174

SMILES CCc1nc2ccc(nn2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CC[C@@H](C1)NCC(=O)N1CC(O)C1

InChI Key InChIKey=ZNGUALNMUMDXTP-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354506   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM354506((S)-2-((2-ethyl-6- (3-(2-(3- hydroxyazetidin-1- yl...)
Affinity DataIC50:  55nMAssay Description:Compound IC50 values are determined in a fluorescent hENPP2 (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotax...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent