BDBM354703 Preparation of 4-((2R,5S)-5-((4-cyano-2-fluorophenoxy)methyl)-2-(trifluoromethyl)oxazolidin-3-yl)-2-(trifluoromethyl)benzonitrile::US9809583, Example 11

SMILES Fc1cc(ccc1OC[C@@H]1CN([C@H](O1)C(F)(F)F)c1ccc(C#N)c(c1)C(F)(F)F)C#N

InChI Key InChIKey=MHXJODFJIPSRTG-KBXCAEBGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354703   

TargetAndrogen receptor(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)
Dong-A St

US Patent
LigandPNGBDBM354703(Preparation of 4-((2R,5S)-5-((4-cyano-2-fluorophen...)
Affinity DataIC50:  10.5nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent