BDBM354740 US9815790, 2

SMILES COCCOCCOCCOCCOCCOCCOCCOc1cc(NC2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc2n1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=DIXRYIXTTKWMBM-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 354740   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM354740(US9815790, 2)
Affinity DataEC50:  480nMAssay Description:Cells plated the day prior to the assay in clear bottom plates were viewed on an inverse microscope to ensure confluency in the range of 60-75%. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM354740(US9815790, 2)
Affinity DataEC50:  5.90E+3nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM354740(US9815790, 2)
Affinity DataEC50:  457nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM354740(US9815790, 2)
Affinity DataEC50:  5.57E+3nMAssay Description:Cells plated the day prior to the assay in clear bottom plates were viewed on an inverse microscope to ensure confluency in the range of 60-75%. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent