BDBM354752 Preparation of 5-(3-(3-chloro-4-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-2-amine ::US10485800, Example 29::US9814704, Example 29

SMILES Nc1ccc(cn1)-c1cnc2[nH]cc(-c3ccc(F)c(Cl)c3)c2c1

InChI Key InChIKey=OBMUXACEERMUCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354752   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM354752(Preparation of 5-(3-(3-chloro-4-fluorophenyl)-1H-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM354752(Preparation of 5-(3-(3-chloro-4-fluorophenyl)-1H-p...)
Affinity DataIC50: >1.00E+3nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent