BDBM354777 6-(3-hydroxyphenyl)-1-(1H- indol-5-yl)-1H-imidazo[4,5- b]pyrazin-2(3H)-one::US10485800, Example 54::US9814704, Example 54
SMILES Oc1cccc(c1)-c1cnc2[nH]c(=O)n(-c3ccc4[nH]ccc4c3)c2n1
InChI Key InChIKey=KHPQEDSQFJNEMB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354777
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester
US Patent
The University Of Rochester
US Patent
Affinity DataIC50: 550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester
US Patent
The University Of Rochester
US Patent
Affinity DataIC50: 550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair