BDBM354813 1-(1H-indazol-6-yl)-6- (3,4,5-trimethoxyphenyl)- 1H-imidazo[4,5-b]pyrazin- 2(3H)-one::US10485800, Example 90::US9814704, Example 90
SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]c(=O)n(-c3ccc4cn[nH]c4c3)c2n1
InChI Key InChIKey=BNETYKOYOKDQQO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354813
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester
US Patent
The University of Rochester
US Patent
Affinity DataIC50: 550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University of Rochester
US Patent
The University of Rochester
US Patent
Affinity DataIC50: 550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair