BDBM354846 US10485800, Example 123::US9814704, Example 123

SMILES COc1cc(cc(OC)c1OC)-c1cnc2NC(=O)C(CC3CC3)(CC3CC3)c2c1

InChI Key InChIKey=PXEBCKJMBGGJJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354846   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM354846(US10485800, Example 123 | US9814704, Example 123)
Affinity DataIC50:  550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM354846(US10485800, Example 123 | US9814704, Example 123)
Affinity DataIC50:  550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent