BDBM354880 Preparation of 4-{5-[4-(4-acetyl-piperazin-1-ylmethyl)-phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}-benzamide::US10485800, Example 157::US9814704, Example 157
SMILES CC(=O)N1CCN(Cc2ccc(cc2)-c2cnc3[nH]cc(-c4ccc(cc4)C(N)=O)c3c2)CC1
InChI Key InChIKey=YAEZGCXSMFMCKO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 354880
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester
US Patent
The University Of Rochester
US Patent
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester
US Patent
The University Of Rochester
US Patent
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair