BDBM354883 Preparation of 2-phenyl-N-{4-[5-(3,4,5-trimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-benzyl}-acetamide::US10485800, Example 160::US9814704, Example 160

SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(CNC(=O)Cc4ccccc4)cc3)c2c1

InChI Key InChIKey=CLEWYUJEELRYOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 354883   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM354883(Preparation of 2-phenyl-N-{4-[5-(3,4,5-trimethoxy-...)
Affinity DataIC50:  550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM354883(Preparation of 2-phenyl-N-{4-[5-(3,4,5-trimethoxy-...)
Affinity DataIC50:  550nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent