BDBM35532 symmetric dicoumarol analogue, 8

SMILES Oc1c(Cc2c(O)c3cc(Cl)ccc3oc2=O)c(=O)oc2ccc(Cl)cc12

InChI Key InChIKey=PLTAUBVYMSAINB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35532   

TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University Of Manchester

LigandPNGBDBM35532(symmetric dicoumarol analogue, 8)
Affinity DataIC50:  9nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Homo sapiens (Human))
University Of Manchester

LigandPNGBDBM35532(symmetric dicoumarol analogue, 8)
Affinity DataIC50:  6.25E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed