BDBM355673 1-{2-[(1R,3S,5R)-3-((1S,2S)-2-fluoro-2-phenyl-cyclopropylcarbamoyl)-2-aza-bicyclo[3.1.0]hex-2-yl]-2-oxo-ethyl}-1H-indazole-3-carboxylic acid amide::US9815819, 38

SMILES NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H]2C[C@]2(F)c2ccccc2)c2ccccc12

InChI Key InChIKey=TUONQBRSRDDMDZ-XZJLILLNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 355673   

TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM355673(1-{2-[(1R,3S,5R)-3-((1S,2S)-2-fluoro-2-phenyl-cycl...)
Affinity DataIC50:  635nMAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent