BDBM355770 N-Cyclopropyl-3-(2,3-dihydro-1H-inden-2-yl)-3H-imidazo[4,5-b]pyridine-2-carboxamide::US9815832, 47

SMILES O=C(NC1CC1)c1nc2cccnc2n1C1Cc2ccccc2C1

InChI Key InChIKey=NDIWSQMLTOTSFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355770   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM355770(N-Cyclopropyl-3-(2,3-dihydro-1H-inden-2-yl)-3H-imi...)
Affinity DataIC50:  6.39E+3nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM355770(N-Cyclopropyl-3-(2,3-dihydro-1H-inden-2-yl)-3H-imi...)
Affinity DataIC50:  1.26E+3nMAssay Description:The PDE4B and 4D assays use scintillation proximity assay (SPA) technology to measure the inhibition of human recombinant PDE4B and PDE4D enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent