BDBM355818 US9815836, Compound 3::US9815836, Compound 35
SMILES Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCCCCCNC(=O)c2n1)c3
InChI Key InChIKey=DEQPRWCETBREMX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 355818
TargetInterleukin-1 receptor-associated kinase 1 [194-712](Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataIC50: 550nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712))In this assay, IRAK1 hydrolyses ATP and autophosphorylates. Measurement of IRAK...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 1 [194-712](Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataIC50: 550nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712))In this assay, IRAK1 hydrolyses ATP and autophosphorylates. Measurement of IRAK...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair