BDBM355823 US9815836, Compound 8

SMILES Cn1cc2NC(=O)c3cccc(n3)-c3cnn(CCOC(=O)N4CCOC(C4)CNC(=O)c2n1)c3

InChI Key InChIKey=QJYCHNPBBAGVAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 355823   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM355823(US9815836, Compound 8)
Affinity DataIC50:  550nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 1 [194-712](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM355823(US9815836, Compound 8)
Affinity DataIC50: >5.00E+3nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712))In this assay, IRAK1 hydrolyses ATP and autophosphorylates. Measurement of IRAK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent