BDBM356172 2-fluoro-N-(5-(2- hydroxypropan-2-yl)-6'-phenyl- [2,3'-bipyridin]-5'-yl)-5-(1- methyl-1H-pyrazol-3-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 172

SMILES Cn1ccc(n1)-c1cc(C(=O)Nc2cc(cnc2-c2ccccc2)-c2ccc(cn2)C(C)(C)O)c(F)cc1C(F)(F)F

InChI Key InChIKey=QVEREYMZYJNVPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356172   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356172(2-fluoro-N-(5-(2- hydroxypropan-2-yl)-6'-phenyl- [...)
Affinity DataIC50:  0.260nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent