BDBM356230 US10604535, Example 2B::US9815850, Compound 2::US9815850, Compound 2A::US9815850, Compound 2B::US9896458, No. 2B
SMILES CN1c2ccccc2C(F)CC(NC(=O)c2cc(Cc3ccccc3)on2)C1=O
InChI Key InChIKey=KUOTXTYJDGYCAZ-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 356230
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:Test compounds were diluted in DMSO and 0.1 μL of solution was dispensed to each well of a 384-well white solid microplate. The assay buffer was...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:Test compounds were diluted in DMSO and 0.1 μL of solution was dispensed to each well of a 384-well white solid microplate. The assay buffer was...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:Test compounds were diluted in DMSO and 0.1 μL of solution was dispensed to each well of a 384-well white solid microplate. The assay buffer was...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:Assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10.1 μl/well using 10 nM of GS...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Fluorescent polarization binding assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:Assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10.1 μl/well using 10 nM of GS...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:Assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10.1 μl/well using 10 nM of GS...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Fluorescent polarization binding assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Fluorescent polarization binding assay was performed in polystyrene low volume 384-well black plate, at Room Temperature (RT) in a final volume of 10...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Denali Therapeutics
US Patent
Denali Therapeutics
US Patent
Affinity DataIC50: 500nMAssay Description:ollowing this reaction, 10 uL of ADP-Glo reagent (Promega) was added to each well and incubated for 40 min at room temperature. This stops the kinase...More data for this Ligand-Target Pair