BDBM356589 N-[3-(7-{1-[3-(Cyanomethyl)-1-(cyclopropylacetyl)azetidin-3-yl]-1H-pyrazol-4-yl}imidazo[1,2-b]pyridazin-3-yl)phenyl]-N′-(2,2,2-trifluoroethyl)urea::US10213427, Example 78

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(cnn12)C(\C=N)=C\NC1(CC#N)CN(C1)C(=O)CC1CC1

InChI Key InChIKey=GWFZRJDRJRZRQL-HLTGJRPVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356589   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM356589(N-[3-(7-{1-[3-(Cyanomethyl)-1-(cyclopropylacetyl)a...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent