BDBM356720 (1R,4S)-2-((R)-3- (3,6-difluoro-9H- carbazol-9-yl)-2- hydroxypropyl)- 2-azabi- cyclo[2.2.1]heptan- 3-one::US10214507, Compound 105::US10759777, Compound 105

SMILES O[C@@H](CN1[C@@H]2CC[C@@H](C2)C1=O)Cn1c2ccc(F)cc2c2cc(F)ccc12

InChI Key InChIKey=BEERPRMSTNISRY-MAZHCROVSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356720   

TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356720((1R,4S)-2-((R)-3- (3,6-difluoro-9H- carbazol-9-yl)...)
Affinity DataEC50:  54nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356720((1R,4S)-2-((R)-3- (3,6-difluoro-9H- carbazol-9-yl)...)
Affinity DataEC50:  54nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent