BDBM356821 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(1R,4R,5R,6S)-5,6-dihydroxybicyclo[2.2.1]hept-2-yl]methoxy}-3-nitrophenyl)sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide::US10213433, Compound 203::US11369599, Compound 203

SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(OCC4C[C@@H]5C[C@H]4[C@H](O)[C@@H]5O)c(c3)[N+]([O-])=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1

InChI Key InChIKey=PBWXDNYODFLHSA-ZCXBXHLPSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356821   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM356821(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:The inhibition constant (Ki) for binding of representative compounds to Bcl-2 protein, as determined by a TR-FRET (Time-Resolved Fluorescence-Resonan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM356821(4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-e...)
Affinity DataKi: <0.0100nMAssay Description:TR-FRET (Time-Resolved Fluorescence-Resonance-Energy-Transfer) assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent