BDBM356924 (S)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)-5- methylpyrrolidin-2- one::US10214507, Compound 112::US10759777, Compound 112

SMILES C[C@H]1CCC(=O)N1C[C@H](O)Cn1c2ccccc2c2ccccc12

InChI Key InChIKey=XSVYVGURCRBCTD-GJZGRUSLSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356924   

TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356924((S)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)...)
Affinity DataEC50:  470nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356924((S)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxypropyl)...)
Affinity DataEC50:  470nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent