BDBM356962 (S)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxy-2- methylpropyl)-3- fluoropyrrolidin-2- one::US10214507, Compound 128::US10759777, Compound 128

SMILES CC(O)(CN1CC[C@H](F)C1=O)Cn1c2ccccc2c2ccccc12

InChI Key InChIKey=FJVWQOQSMAKEAY-DJZRFWRSSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356962   

TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356962((S)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxy-2- met...)
Affinity DataEC50:  172nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356962((S)-1-((R)-3-(9H- carbazol-9-yl)-2- hydroxy-2- met...)
Affinity DataEC50:  172nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent