BDBM356988 (R)-1-((R)-3-(3,6- difluoro-9H- carbazol-9-yl)-2- hydroxypropyl)-4- methylimidazolidin- 2-one::US10214507, Compound 136::US10759777, Compound 136

SMILES C[C@@H]1CN(C[C@H](O)Cn2c3ccc(F)cc3c3cc(F)ccc23)C(=O)N1

InChI Key InChIKey=LWBGFYMVAIWBQD-RISCZKNCSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356988   

TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356988((R)-1-((R)-3-(3,6- difluoro-9H- carbazol-9-yl)-2- ...)
Affinity DataEC50:  826nMAssay Description:In brief, stable U20S reporter cells harboring Per2-dLuc were plated at a density of 30,000 cells/well in Corning 96-well, solid white, flat bottom, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeriod circadian protein homolog 2(Homo sapiens (Human))
Synchronicity Pharma

US Patent
LigandPNGBDBM356988((R)-1-((R)-3-(3,6- difluoro-9H- carbazol-9-yl)-2- ...)
Affinity DataEC50:  826nMAssay Description:Compounds were screened by using a high-throughput circadian assay system as previously described in Zhang, E. E. et al. Cell, 2009, 139, 199-210. In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent