BDBM356995 5-Amino-N-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide::US10214509, Example 1

SMILES COc1ccccc1-n1ncc(C(=O)Nc2ccc(Cl)cc2)c1N

InChI Key InChIKey=FDUPGWUBHRSPJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 356995   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM356995(5-Amino-N-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-...)
Affinity DataIC50:  2.10E+4nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM356995(5-Amino-N-(4-chlorophenyl)-1-(2-methoxyphenyl)-1H-...)
Affinity DataIC50:  700nMAssay Description:Cell LinesStable cell lines expressing the full-length protein of the voltage-gated sodium channels Nav1.7 or Nav1.5, with or without one beta-1, bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent